Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.

Eitemau Tebyg

• Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.
  gan: Cockman, M, et al.
  Cyhoeddwyd: (2000)
• Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing.
  gan: Mole, D, et al.
  Cyhoeddwyd: (2001)
• Chemical basis for the selectivity of the von Hippel Lindau tumor suppressor pVHL for prolyl-hydroxylated HIF-1alpha.
  gan: Illingworth, C, et al.
  Cyhoeddwyd: (2010)
• Interaction of hydroxylated collagen IV with the von hippel-lindau tumor suppressor.
  gan: Grosfeld, A, et al.
  Cyhoeddwyd: (2007)
• The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis.
  gan: Pugh, C, et al.
  Cyhoeddwyd: (2003)