Immunodominance of poxviral-specific CTL in a human trial of recombinant-modified vaccinia Ankara.

Many recombinant poxviral vaccines are currently in clinical trials for cancer and infectious diseases. However, these agents have failed to generate T cell responses specific for recombinant gene products at levels comparable with T cell responses associated with natural viral infections. The recen...

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Main Authors: Smith, C, Mirza, F, Pasquetto, V, Tscharke, D, Palmowski, M, Dunbar, P, Sette, A, Harris, A, Cerundolo, V
格式: Journal article
语言:English
出版: 2005