Regulatory region single nucleotide polymorphisms of the apolipoprotein E gene and the rate of cognitive decline in Alzheimer's disease.

Regulatory region single nucleotide polymorphisms of the apolipoprotein E gene and the rate of cognitive decline in Alzheimer's disease.

The aim of this study was to investigate whether single nucleotide polymorphisms (SNPs) in the regulatory regions of the apolipoprotein E (APOE) gene modify the well-established epsilon4-associated risk for Alzheimer's disease (AD). Sequencing of the APOE gene regulatory regions revealed four p...

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Bibliographic Details
Main Authors: Belbin, O, Dunn, J, Ling, Y, Morgan, L, Chappell, S, Beaumont, H, Warden, D, Smith, D, Kalsheker, N, Morgan, K
Format: Journal article
Language:English
Published: 2007

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