Escape is a more common mechanism than avidity reduction for evasion of CD8+ T cell responses in primary human immunodeficiency virus type 1 infection.

BACKGROUND: CD8+ T cells play an important role in control of viral replication during acute and early human immunodeficiency virus type 1 (HIV-1) infection, contributing to containment of the acute viral burst and establishment of the prognostically-important persisting viral load. Understanding m...

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Bibliographic Details
Main Authors: Turnbull, E, Baalwa, J, Conrod, K, Wang, S, Wei, X, Wong, M, Turner, J, Pellegrino, P, Williams, I, Shaw, G, Borrow, P
Format: Journal article
Language:English
Published: 2011