Ligation of CD40 rescues Ramos-Burkitt lymphoma B cells from calcium ionophore- and antigen receptor-triggered apoptosis by inhibiting activation of the cysteine protease CPP32/Yama and cleavage of its substrate PARP
The new and growing family of interleukin-1β-converting enzyme (ICE) cysteine proteases are now recognised to be major effectors of cellular death by apoptosis. Like other members of this family, the CPP32/Yama proform is activated by processing to its active heterodimeric enzyme or apopain when it...
| المؤلفون الرئيسيون: | , |
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| مؤلفون آخرون: | |
| التنسيق: | Journal article |
| اللغة: | English |
| منشور في: |
Elsevier
1996
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| الموضوعات: |