T cell re-targeting to EBV antigens following TCR gene transfer: CD28-containing receptors mediate enhanced antigen-specific IFNgamma production.

T cell re-targeting to EBV antigens following TCR gene transfer: CD28-containing receptors mediate enhanced antigen-specific IFNgamma production.

EBV is associated with a broad range of malignancies. Adoptive immunotherapy of these tumors with EBV-specific CTL proved useful. We generated a panel of primary human T cells specific to various EBV antigens (i.e. Epstein-Barr nuclear antigen 3A, 3B and BamHI-M leftward reading frame) via transfer...

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Bibliographic Details
Main Authors:	Schaft, N, Lankiewicz, B, Drexhage, J, Berrevoets, C, Moss, D, Levitsky, V, Bonneville, M, Lee, S, Mcmichael, A, Gratama, J, Bolhuis, R, Willemsen, R, Debets, R
Format:	Journal article
Language:	English
Published:	2006

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