Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response.

CD8+ cytotoxic T lymphocytes (CTLs) play an important role in containment of virus replication in primary human immunodeficiency virus (HIV) infection. HIV's ability to mutate to escape from CTL pressure is increasingly recognized; but comprehensive studies of escape from the CD8 T cell respons...

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Detalles Bibliográficos
Main Authors: Jones, N, Wei, X, Flower, DR, Wong, M, Michor, F, Saag, MS, Hahn, B, Nowak, M, Shaw, G, Borrow, P
Formato: Journal article
Idioma:English
Publicado: 2004