Development and implementation of a 3d-HDR brachytherapy program for cervical cancer in a sub-Saharan African centre
<p><strong>BACKGROUND: </strong>Cervical cancer is the second most common cancer among women in Nigeria where, the gap between need for, and access to, radiation therapy including brachytherapy is significant. This report documents the implementation of the first three-dim...
| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
2024
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| _version_ | 1824458756302307328 |
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| author | Joseph, A Balogun, O Adegboyega, B Salako, O Irabor, OC Ajose, A Adeneye, S Alabi, A Ohazurike, E Ogamba, CF Oladipo, A Fagbemide, O Habeebu, M Puthoff, D Onitilo, A Ngwa, W Nwachukwu, C |
| author_facet | Joseph, A Balogun, O Adegboyega, B Salako, O Irabor, OC Ajose, A Adeneye, S Alabi, A Ohazurike, E Ogamba, CF Oladipo, A Fagbemide, O Habeebu, M Puthoff, D Onitilo, A Ngwa, W Nwachukwu, C |
| author_sort | Joseph, A |
| collection | OXFORD |
| description | <p><strong>BACKGROUND: </strong>Cervical cancer is the second most common cancer among women in Nigeria where, the gap between need for, and access to, radiation therapy including brachytherapy is significant. This report documents the implementation of the first three-dimensional high-dose-rate (3D-HDR) brachytherapy service for cervical cancer in Nigeria.</p>
<p><strong>PURPOSE: </strong>This report details the steps taken to implement the 3D-HDR brachytherapy program, the challenges faced, and the adaptive strategies employed to overcome them. Our objective is to provide a guide for teams and centers in similar resource-restricted settings to implement 3D-HDR brachytherapy services, by leveraging our shared experience and lessons learned.</p>
<p><strong>METHOD AND METERIALS: </strong>The implementation process required investment in infrastructure: creating a dedicated brachytherapy suite equipped with modern technology; and human capital: conducting both virtual and hands-on training for staff; and involving international experts during the initial treatment phases. Quality assurance protocols were established to ensure the accuracy and safety of treatments. Key adaptations included extensive remote training, international experts flying in for the initiation phase, and preemptively re-ordering the radioisotope to prevent delays.</p>
<p><strong>RESULTS: </strong>The 3D-HDR brachytherapy program was successfully implemented, with five cases treated in the first 2 months despite challenges such as high equipment costs, expertise and proficiency needs, and source replacement delays. Continuous training and quality assurance measures ensured the program's sustainability and effectiveness.</p>
<p><strong>CONCLUSIONS: </strong>Implementing a 3D-HDR brachytherapy program in a system with restricted resources is possible with thorough planning, flexible strategies, and adaptive measures. We document our experience to provide insights for other institutions aiming to establish similar programs. Collaboration and innovative financial strategies are essential for ensuring sustainable access to cancer treatment in the region. Strategies such as remote training and proactive resource management, are critical for overcoming implementation barriers.</p> |
| first_indexed | 2025-02-19T04:30:57Z |
| format | Journal article |
| id | oxford-uuid:03968ad7-e2af-4985-99e0-03cc25924840 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2025-02-19T04:30:57Z |
| publishDate | 2024 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:03968ad7-e2af-4985-99e0-03cc259248402025-01-08T11:31:37ZDevelopment and implementation of a 3d-HDR brachytherapy program for cervical cancer in a sub-Saharan African centreJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:03968ad7-e2af-4985-99e0-03cc25924840EnglishSymplectic ElementsElsevier2024Joseph, ABalogun, OAdegboyega, BSalako, OIrabor, OCAjose, AAdeneye, SAlabi, AOhazurike, EOgamba, CFOladipo, AFagbemide, OHabeebu, MPuthoff, DOnitilo, ANgwa, WNwachukwu, C<p><strong>BACKGROUND: </strong>Cervical cancer is the second most common cancer among women in Nigeria where, the gap between need for, and access to, radiation therapy including brachytherapy is significant. This report documents the implementation of the first three-dimensional high-dose-rate (3D-HDR) brachytherapy service for cervical cancer in Nigeria.</p> <p><strong>PURPOSE: </strong>This report details the steps taken to implement the 3D-HDR brachytherapy program, the challenges faced, and the adaptive strategies employed to overcome them. Our objective is to provide a guide for teams and centers in similar resource-restricted settings to implement 3D-HDR brachytherapy services, by leveraging our shared experience and lessons learned.</p> <p><strong>METHOD AND METERIALS: </strong>The implementation process required investment in infrastructure: creating a dedicated brachytherapy suite equipped with modern technology; and human capital: conducting both virtual and hands-on training for staff; and involving international experts during the initial treatment phases. Quality assurance protocols were established to ensure the accuracy and safety of treatments. Key adaptations included extensive remote training, international experts flying in for the initiation phase, and preemptively re-ordering the radioisotope to prevent delays.</p> <p><strong>RESULTS: </strong>The 3D-HDR brachytherapy program was successfully implemented, with five cases treated in the first 2 months despite challenges such as high equipment costs, expertise and proficiency needs, and source replacement delays. Continuous training and quality assurance measures ensured the program's sustainability and effectiveness.</p> <p><strong>CONCLUSIONS: </strong>Implementing a 3D-HDR brachytherapy program in a system with restricted resources is possible with thorough planning, flexible strategies, and adaptive measures. We document our experience to provide insights for other institutions aiming to establish similar programs. Collaboration and innovative financial strategies are essential for ensuring sustainable access to cancer treatment in the region. Strategies such as remote training and proactive resource management, are critical for overcoming implementation barriers.</p> |
| spellingShingle | Joseph, A Balogun, O Adegboyega, B Salako, O Irabor, OC Ajose, A Adeneye, S Alabi, A Ohazurike, E Ogamba, CF Oladipo, A Fagbemide, O Habeebu, M Puthoff, D Onitilo, A Ngwa, W Nwachukwu, C Development and implementation of a 3d-HDR brachytherapy program for cervical cancer in a sub-Saharan African centre |
| title | Development and implementation of a 3d-HDR brachytherapy program for cervical cancer in a sub-Saharan African centre |
| title_full | Development and implementation of a 3d-HDR brachytherapy program for cervical cancer in a sub-Saharan African centre |
| title_fullStr | Development and implementation of a 3d-HDR brachytherapy program for cervical cancer in a sub-Saharan African centre |
| title_full_unstemmed | Development and implementation of a 3d-HDR brachytherapy program for cervical cancer in a sub-Saharan African centre |
| title_short | Development and implementation of a 3d-HDR brachytherapy program for cervical cancer in a sub-Saharan African centre |
| title_sort | development and implementation of a 3d hdr brachytherapy program for cervical cancer in a sub saharan african centre |
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