DNA replication licensing factors and aurora kinases are linked to aneuploidy and clinical outcome in epithelial ovarian carcinoma.

DNA replication licensing factors and aurora kinases are linked to aneuploidy and clinical outcome in epithelial ovarian carcinoma.

PURPOSE: DNA replication licensing factors and Aurora kinases play critical roles in maintaining genomic integrity. We used multiparameter analyses of these cell cycle regulatory proteins to investigate their role in the progression of epithelial ovarian carcinoma (EOC). EXPERIMENTAL DESIGN: In a c...

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Detalles Bibliográficos
Autores principales: Kulkarni, A, Loddo, M, Leo, E, Rashid, M, Eward, K, Fanshawe, T, Butcher, J, Frost, A, Ledermann, J, Williams, G, Stoeber, K
Formato: Journal article
Lenguaje:English
Publicado: 2007

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