Survival and quality of life in patients with protracted recovery from cardiac surgery. Can we predict poor outcome?

Of all the 2256 adult cardiac surgical patients operated upon during a 12-month period from 1st February 1992 in three units, only 162 (7.2%) spent more than 48 h in the intensive care unit (ICU) (median 6 days, range 3-90). There were 47 deaths in ICU, 7 more before hospital discharge, and a furthe...

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Main Authors: Treasure, T, Holmes, L, Loughead, K, Gallivan, S
Format: Journal article
Language:English
Published: 1995
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author Treasure, T
Holmes, L
Loughead, K
Gallivan, S
author_facet Treasure, T
Holmes, L
Loughead, K
Gallivan, S
author_sort Treasure, T
collection OXFORD
description Of all the 2256 adult cardiac surgical patients operated upon during a 12-month period from 1st February 1992 in three units, only 162 (7.2%) spent more than 48 h in the intensive care unit (ICU) (median 6 days, range 3-90). There were 47 deaths in ICU, 7 more before hospital discharge, and a further 10 before the study end-point of one year after surgery. All 98 1-year survivors were at home with 86 of them reporting their quality of life, on formal evaluation, to be within the reference range which we have established for a less complicated cohort of cardiac surgical patients. Prospectively collected physiological measurements were used in a mathematical model to test how well we could predict which patients will die and which of the survivors have a poor quality of life. The algorithm performs well for cardiac surgery patients with a specificity of 98%. If treatment had been withdrawn when death or poor quality of life became predictable, the maximum number of ICU bed days that could be freed was of the order of 2%. The plight of these patients is distressing, but most survive and do well and they are infrequent compared with the large majority who survive to leave hospital after a short ICU stay.
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spelling oxford-uuid:03d17c48-3208-414a-b969-8e497596b2a62022-03-26T08:48:27ZSurvival and quality of life in patients with protracted recovery from cardiac surgery. Can we predict poor outcome?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:03d17c48-3208-414a-b969-8e497596b2a6EnglishSymplectic Elements at Oxford1995Treasure, THolmes, LLoughead, KGallivan, SOf all the 2256 adult cardiac surgical patients operated upon during a 12-month period from 1st February 1992 in three units, only 162 (7.2%) spent more than 48 h in the intensive care unit (ICU) (median 6 days, range 3-90). There were 47 deaths in ICU, 7 more before hospital discharge, and a further 10 before the study end-point of one year after surgery. All 98 1-year survivors were at home with 86 of them reporting their quality of life, on formal evaluation, to be within the reference range which we have established for a less complicated cohort of cardiac surgical patients. Prospectively collected physiological measurements were used in a mathematical model to test how well we could predict which patients will die and which of the survivors have a poor quality of life. The algorithm performs well for cardiac surgery patients with a specificity of 98%. If treatment had been withdrawn when death or poor quality of life became predictable, the maximum number of ICU bed days that could be freed was of the order of 2%. The plight of these patients is distressing, but most survive and do well and they are infrequent compared with the large majority who survive to leave hospital after a short ICU stay.
spellingShingle Treasure, T
Holmes, L
Loughead, K
Gallivan, S
Survival and quality of life in patients with protracted recovery from cardiac surgery. Can we predict poor outcome?
title Survival and quality of life in patients with protracted recovery from cardiac surgery. Can we predict poor outcome?
title_full Survival and quality of life in patients with protracted recovery from cardiac surgery. Can we predict poor outcome?
title_fullStr Survival and quality of life in patients with protracted recovery from cardiac surgery. Can we predict poor outcome?
title_full_unstemmed Survival and quality of life in patients with protracted recovery from cardiac surgery. Can we predict poor outcome?
title_short Survival and quality of life in patients with protracted recovery from cardiac surgery. Can we predict poor outcome?
title_sort survival and quality of life in patients with protracted recovery from cardiac surgery can we predict poor outcome
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