Expression of an efficient small molecular weight tumour necrosis factor/lymphotoxin antagonist.

TNF-alpha and lymphotoxin are proinflammatory cytokines that are non-homologous in sequence, have similar homotrimeric structure and they exert their biological activity by aggregating two types of shared cell surface receptors. The natural inhibitors of TNF and lymphotoxin are the shed extracellula...

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Detalhes bibliográficos
Main Authors: Neve, R, Kissonerghis, M, Clark, J, Feldmann, M, Chernajovsky, Y
Formato: Journal article
Idioma:English
Publicado em: 1996