IN VIVO ENRICHMENT OF REGULATORY T CELLS BY BCL-2/BCL-XL INHIBITION PROMOTES TOLERANCE IN ALLOTRANSPLANTATION

Eitemau Tebyg

• Distinctive expression of Bcl-2 factors in regulatory T cells determines a pharmacological target to induce immunological tolerance
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  Cyhoeddwyd: (2016-03-01)
• Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
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• MDM2-BCL-XL PROTACs enable degradation of BCL-XL and stabilization of p53
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  Cyhoeddwyd: (2022-08-01)
• Inhibition of Antiapoptotic BCL-XL, BCL-2, and MCL-1 Proteins by Small Molecule Mimetics
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• Bcl-xL in neuroprotection and plasticity
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  Cyhoeddwyd: (2014-09-01)