Feedback Control Architecture and the Bacterial Chemotaxis Network
This paper investigates the chemotaxis behavior of the bacterium R. sphaeroides. We review the results of a recent study comparing different possible mathematical models of this bacterium's chemotaxis decision mechanisms. It was found that only one of the aforesaid models could explain the expe...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Public Library of Science
2011
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| _version_ | 1826257159530217472 |
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| author | Hamadeh, A Roberts, MAJ August, E McSharry, P Maini, P Armitage, J Papachristodoulou, A |
| author_facet | Hamadeh, A Roberts, MAJ August, E McSharry, P Maini, P Armitage, J Papachristodoulou, A |
| author_sort | Hamadeh, A |
| collection | OXFORD |
| description | This paper investigates the chemotaxis behavior of the bacterium R. sphaeroides. We review the results of a recent study comparing different possible mathematical models of this bacterium's chemotaxis decision mechanisms. It was found that only one of the aforesaid models could explain the experimental chemotactic response data. From a control theoretic perspective, we show that, compared to the other models posed, this model exhibits better and more robust chemotactic performance. This decision mechanism parallels a feedback architecture that has been used extensively to improve performance in engineered systems. We suggest that this mechanism may play a role in maintaining the chemotactic performance of this and potentially other bacteria. |
| first_indexed | 2024-03-06T18:13:42Z |
| format | Journal article |
| id | oxford-uuid:03e18fda-c590-4a44-b450-f0db9526d0fe |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T18:13:42Z |
| publishDate | 2011 |
| publisher | Public Library of Science |
| record_format | dspace |
| spelling | oxford-uuid:03e18fda-c590-4a44-b450-f0db9526d0fe2022-03-26T08:48:43ZFeedback Control Architecture and the Bacterial Chemotaxis NetworkJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:03e18fda-c590-4a44-b450-f0db9526d0feEnglishSymplectic Elements at OxfordPublic Library of Science2011Hamadeh, ARoberts, MAJAugust, EMcSharry, PMaini, PArmitage, JPapachristodoulou, AThis paper investigates the chemotaxis behavior of the bacterium R. sphaeroides. We review the results of a recent study comparing different possible mathematical models of this bacterium's chemotaxis decision mechanisms. It was found that only one of the aforesaid models could explain the experimental chemotactic response data. From a control theoretic perspective, we show that, compared to the other models posed, this model exhibits better and more robust chemotactic performance. This decision mechanism parallels a feedback architecture that has been used extensively to improve performance in engineered systems. We suggest that this mechanism may play a role in maintaining the chemotactic performance of this and potentially other bacteria. |
| spellingShingle | Hamadeh, A Roberts, MAJ August, E McSharry, P Maini, P Armitage, J Papachristodoulou, A Feedback Control Architecture and the Bacterial Chemotaxis Network |
| title | Feedback Control Architecture and the Bacterial Chemotaxis Network |
| title_full | Feedback Control Architecture and the Bacterial Chemotaxis Network |
| title_fullStr | Feedback Control Architecture and the Bacterial Chemotaxis Network |
| title_full_unstemmed | Feedback Control Architecture and the Bacterial Chemotaxis Network |
| title_short | Feedback Control Architecture and the Bacterial Chemotaxis Network |
| title_sort | feedback control architecture and the bacterial chemotaxis network |
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