A synthesis of dioctanoyl phosphatidylinositol
A synthesis of the naturally occurring enantiomer of phosphatidylinositol is reported. A resolution strategy, using camphor as a chiral auxiliary is employed to obtain the desired, enantiomerically pure, inositol derivative. Dioctanoyl lipid chains are appended to the molecule, which are shorter tha...
Huvudupphovsmän: | , , , |
---|---|
Materialtyp: | Journal article |
Språk: | English |
Publicerad: |
2009
|
_version_ | 1826257174050897920 |
---|---|
author | Elliott, T Nemeth, J Swain, SA Conway, S |
author_facet | Elliott, T Nemeth, J Swain, SA Conway, S |
author_sort | Elliott, T |
collection | OXFORD |
description | A synthesis of the naturally occurring enantiomer of phosphatidylinositol is reported. A resolution strategy, using camphor as a chiral auxiliary is employed to obtain the desired, enantiomerically pure, inositol derivative. Dioctanoyl lipid chains are appended to the molecule, which are shorter than the naturally occurring lipid chains, providing the molecule with enhanced water solubility. © 2009 Elsevier Ltd. All rights reserved. |
first_indexed | 2024-03-06T18:13:56Z |
format | Journal article |
id | oxford-uuid:03f6315a-16d4-4a1e-9d2b-422eb5648ee0 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T18:13:56Z |
publishDate | 2009 |
record_format | dspace |
spelling | oxford-uuid:03f6315a-16d4-4a1e-9d2b-422eb5648ee02022-03-26T08:49:22ZA synthesis of dioctanoyl phosphatidylinositolJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:03f6315a-16d4-4a1e-9d2b-422eb5648ee0EnglishSymplectic Elements at Oxford2009Elliott, TNemeth, JSwain, SAConway, SA synthesis of the naturally occurring enantiomer of phosphatidylinositol is reported. A resolution strategy, using camphor as a chiral auxiliary is employed to obtain the desired, enantiomerically pure, inositol derivative. Dioctanoyl lipid chains are appended to the molecule, which are shorter than the naturally occurring lipid chains, providing the molecule with enhanced water solubility. © 2009 Elsevier Ltd. All rights reserved. |
spellingShingle | Elliott, T Nemeth, J Swain, SA Conway, S A synthesis of dioctanoyl phosphatidylinositol |
title | A synthesis of dioctanoyl phosphatidylinositol |
title_full | A synthesis of dioctanoyl phosphatidylinositol |
title_fullStr | A synthesis of dioctanoyl phosphatidylinositol |
title_full_unstemmed | A synthesis of dioctanoyl phosphatidylinositol |
title_short | A synthesis of dioctanoyl phosphatidylinositol |
title_sort | synthesis of dioctanoyl phosphatidylinositol |
work_keys_str_mv | AT elliottt asynthesisofdioctanoylphosphatidylinositol AT nemethj asynthesisofdioctanoylphosphatidylinositol AT swainsa asynthesisofdioctanoylphosphatidylinositol AT conways asynthesisofdioctanoylphosphatidylinositol AT elliottt synthesisofdioctanoylphosphatidylinositol AT nemethj synthesisofdioctanoylphosphatidylinositol AT swainsa synthesisofdioctanoylphosphatidylinositol AT conways synthesisofdioctanoylphosphatidylinositol |