A synthesis of dioctanoyl phosphatidylinositol

A synthesis of dioctanoyl phosphatidylinositol

A synthesis of the naturally occurring enantiomer of phosphatidylinositol is reported. A resolution strategy, using camphor as a chiral auxiliary is employed to obtain the desired, enantiomerically pure, inositol derivative. Dioctanoyl lipid chains are appended to the molecule, which are shorter tha...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Elliott, T, Nemeth, J, Swain, SA, Conway, S
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2009

Παρόμοια τεκμήρια

Toward the synthesis of caged cell membrane permeant phosphatidylinositol polyphosphates.
ανά: Johns, M, κ.ά.
Έκδοση: (2004)

Synthesis of deuterated phosphatidylinositol phosphates
ανά: Saunders, A
Έκδοση: (2016)

Synthesis and biological evaluation of phosphatidylinositol phosphate affinity probes.
ανά: Conway, S, κ.ά.
Έκδοση: (2010)

Biology-enabling inositol phosphates, phosphatidylinositol phosphates and derivatives.
ανά: Conway, S, κ.ά.
Έκδοση: (2007)

Glycosyl-phosphatidylinositol molecules of the parasite and the host.
ανά: Ferguson, M, κ.ά.
Έκδοση: (1994)

Development of isotope-enriched phosphatidylinositol-4-and 5-phosphate cellular mass spectrometry probes
ανά: Joffrin, AM, κ.ά.
Έκδοση: (2020)

Lipid droplets formation and their effects on phosphatidylinositol level in yeasts
ανά: Fabrice Mutijima, κ.ά.
Έκδοση: (2020-08-01)

Chemical Synthesis of 6-Azido-6-Deoxy Derivatives of Phosphatidylinositol Containing Different Fatty Acid Chains
ανά: Mosidur Rahaman Molla, κ.ά.
Έκδοση: (2024-10-01)

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate
ανά: Harlan, John E., κ.ά.
Έκδοση: (2012)

Selective regulation of chemosensitivity in glioblastoma by phosphatidylinositol 3-kinase beta
ανά: Kevin J. Pridham, κ.ά.
Έκδοση: (2024-06-01)

Phosphatidylinositol 3-kinase signaling in thymocytes: the need for stringent control.
ανά: Fayard, E, κ.ά.
Έκδοση: (2010)

Structural modeling of phosphatidylinositol 3-kinase-γ with novel derivatives of stilbenoids
ανά: Sagar Rathee, κ.ά.
Έκδοση: (2024-12-01)

Plasma membrane and nuclear phosphatidylinositol 4,5-bisphosphate signalling in cancer
ανά: Agnieszka Chytła, κ.ά.
Έκδοση: (2025-02-01)

Hyperglycemia secondary to phosphatidylinositol-3 kinase (PI3K) inhibition
ανά: Arunan Sriravindrarajah, κ.ά.
Έκδοση: (2024-10-01)

Alpelisib (phosphatidylinositol 3-kinase inhibitor) induced uncontrolled hyperglycemia and colitis
ανά: Sanchit Duhan, κ.ά.
Έκδοση: (2024-06-01)

Pooled analysis of phosphatidylinositol 3-kinase pathway variants and risk of prostate cancer.
ανά: Koutros, S, κ.ά.
Έκδοση: (2010)

Phosphatidylinositol 3-kinase delta pathway: a novel therapeutic target for Sjögren's syndrome
ανά: Nayar, S, κ.ά.
Έκδοση: (2018)

Simulation-based prediction of phosphatidylinositol 4,5-bisphosphate binding to an ion channel.
ανά: Schmidt, MR, κ.ά.
Έκδοση: (2013)

Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment
ανά: Honigmann, A, κ.ά.
Έκδοση: (2013)

Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment.
ανά: Honigmann, A, κ.ά.
Έκδοση: (2013)

Detergent-induced quantitatively limited formation of diacyl phosphatidylinositol dimannoside in Mycobacterium smegmatis
ανά: Claire E. Kitzmiller, κ.ά.
Έκδοση: (2024-07-01)

Acutely Modifying Phosphatidylinositol Phosphates on Endolysosomes Using Chemically Inducible Dimerization Systems
ανά: Wei Sheng Yap, κ.ά.
Έκδοση: (2024-10-01)

Rapid Movement of Palmitoleic Acid from Phosphatidylcholine to Phosphatidylinositol in Activated Human Monocytes
ανά: Miguel A. Bermúdez, κ.ά.
Έκδοση: (2024-06-01)

Role of phosphatidylinositol 3‐kinase signaling pathway in radiation‐induced liver injury
ανά: Lei Xiao, κ.ά.
Έκδοση: (2020-12-01)

Structural characterization of the interaction between a Pleckstrin homology domain and phosphatidylinositol 4,5-bisphosphate
ανά: Harlan, John E., κ.ά.
Έκδοση: (2012)

Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions.
ανά: de Pereda, J, κ.ά.
Έκδοση: (2005)

Interactions of perihperal membrane proteins with phosphatidylinositol lipids: insights from molecular dynamics simulations
ανά: Naughton, F
Έκδοση: (2017)

The phosphatidylinositol-5′ phosphatase synaptojanin1 limits integrin-mediated invasion of Staphylococcus aureus
ανά: Yong Shi, κ.ά.
Έκδοση: (2024-04-01)

A phosphatidylinositol 3-kinase-Pax3 axis regulates Brn-2 expression in melanoma.
ανά: Bonvin, E, κ.ά.
Έκδοση: (2012)

A type II phosphatidylinositol-4-kinase coordinates sorting of cargo polarizing by endocytic recycling
ανά: Anezia Kourkoulou, κ.ά.
Έκδοση: (2024-07-01)

The Phosphatidylinositol 3-Kinase/mTor Pathway as a Therapeutic Target for Brain Aging and Neurodegeneration
ανά: David Heras-Sandoval, κ.ά.
Έκδοση: (2011-08-01)

Structural insights into the inhibition of actin-capping protein by interactions with phosphatidic acid and phosphatidylinositol (4,5)-bisphosphate.
ανά: Roman Pleskot, κ.ά.
Έκδοση: (2012-01-01)

Productive entry of foot-and-mouth disease virus via macropinocytosis independent of phosphatidylinositol 3-kinase
ανά: Han, Shi-Chong, κ.ά.
Έκδοση: (2018)

Interactions of the pleckstrin homology domain with phosphatidylinositol phosphate and membranes: characterization via molecular dynamics simulations.
ανά: Psachoulia, E, κ.ά.
Έκδοση: (2008)

Prognostic role and therapeutic implications of phosphatidylinositol transfer protein cytoplasmic 1 in primary prostate cancer
ανά: Jianming Lu, κ.ά.
Έκδοση: (2024-11-01)

Inhibition of phosphatidylinositol 3‐kinase α (PI3Kα) prevents heterotopic ossification
ανά: José Antonio Valer, κ.ά.
Έκδοση: (2019-08-01)

Pan-phosphatidylinositol 3-kinase inhibition with buparlisib in patients with relapsed or refractory non-Hodgkin lymphoma
ανά: Anas Younes, κ.ά.
Έκδοση: (2017-12-01)

Phosphatidylinositol 4,5-Bisphosphate Is an HCV NS5A Ligand and Mediates Replication of the Viral Genome
ανά: Cho, Nam-Joon, κ.ά.
Έκδοση: (2016)

Phosphatidylinositol 4,5-Bisphosphate Is an HCV NS5A Ligand and Mediates Replication of the Viral Genome
ανά: Cho, Nam-Joon, κ.ά.
Έκδοση: (2016)

Membrane recognition and binding by the phosphatidylinositol phosphate kinase PIP5K1A: a multiscale simulation study
ανά: Amos, S-BTA, κ.ά.
Έκδοση: (2019)