The identification and validation of Auger electron-emitting radiopharmaceuticals targeting telomerase for cancer therapy

<p>Telomerase is expressed in the majority (&gt;85%) of tumours but not in differentiated normal tissue. This enzyme catalyses the elongation of telomeres – a process critical for continued cell proliferation. Telomerase is a potential novel target for molecularly-targeted radiotherapy (mR...

Fuld beskrivelse

Bibliografiske detaljer
Hovedforfatter: Jackson, M
Andre forfattere: Vallis, K
Format: Thesis
Sprog:English
Udgivet: 2013
Fag: