The identification and validation of Auger electron-emitting radiopharmaceuticals targeting telomerase for cancer therapy

<p>Telomerase is expressed in the majority (&gt;85%) of tumours but not in differentiated normal tissue. This enzyme catalyses the elongation of telomeres – a process critical for continued cell proliferation. Telomerase is a potential novel target for molecularly-targeted radiotherapy (mR...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Jackson, M
مؤلفون آخرون: Vallis, K
التنسيق: أطروحة
اللغة:English
منشور في: 2013
الموضوعات: