The identification and validation of Auger electron-emitting radiopharmaceuticals targeting telomerase for cancer therapy

<p>Telomerase is expressed in the majority (&gt;85%) of tumours but not in differentiated normal tissue. This enzyme catalyses the elongation of telomeres – a process critical for continued cell proliferation. Telomerase is a potential novel target for molecularly-targeted radiotherapy (mR...

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Détails bibliographiques
Auteur principal: Jackson, M
Autres auteurs: Vallis, K
Format: Thèse
Langue:English
Publié: 2013
Sujets: