The identification and validation of Auger electron-emitting radiopharmaceuticals targeting telomerase for cancer therapy
<p>Telomerase is expressed in the majority (>85%) of tumours but not in differentiated normal tissue. This enzyme catalyses the elongation of telomeres – a process critical for continued cell proliferation. Telomerase is a potential novel target for molecularly-targeted radiotherapy (mR...
Main Author: | Jackson, M |
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Other Authors: | Vallis, K |
Format: | Thesis |
Language: | English |
Published: |
2013
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Subjects: |
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