The identification and validation of Auger electron-emitting radiopharmaceuticals targeting telomerase for cancer therapy

<p>Telomerase is expressed in the majority (&gt;85%) of tumours but not in differentiated normal tissue. This enzyme catalyses the elongation of telomeres – a process critical for continued cell proliferation. Telomerase is a potential novel target for molecularly-targeted radiotherapy (mR...

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Detalles Bibliográficos
Autor Principal: Jackson, M
Outros autores: Vallis, K
Formato: Thesis
Idioma:English
Publicado: 2013
Subjects: