Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation.
FoxP3(+) confers suppressive properties and is confined to regulatory T cells (T(reg)) that potently inhibit autoreactive immune responses. In the transplant setting, natural CD4(+) T(reg) are critical in controlling alloreactivity and the establishment of tolerance. We now identify an important CD8...
Հիմնական հեղինակներ: | Robb, R, Lineburg, K, Kuns, R, Wilson, Y, Raffelt, N, Olver, S, Varelias, A, Alexander, K, Teal, B, Sparwasser, T, Hammerling, G, Markey, K, Koyama, M, Clouston, A, Engwerda, C, Hill, G, MacDonald, K |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2012
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