A class of 5-nitro-2-furancarboxylamides with potent trypanocidal activity against trypanosoma brucei in vitro

Recently, the World Health Organization approved the nifurtimox–eflornithine combination therapy for the treatment of human African trypanosomiasis, renewing interest in nitroheterocycle therapies for this and associated diseases. In this study, we have synthesized a series of novel 5-nitro-2-furanc...

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Autori principali: Zhou, L, Stewart, G, Rideau, E, Westwood, NJ, Smith, TK
Natura: Journal article
Lingua:English
Pubblicazione: American Chemical Society 2013