A class of 5-nitro-2-furancarboxylamides with potent trypanocidal activity against trypanosoma brucei in vitro

Recently, the World Health Organization approved the nifurtimox–eflornithine combination therapy for the treatment of human African trypanosomiasis, renewing interest in nitroheterocycle therapies for this and associated diseases. In this study, we have synthesized a series of novel 5-nitro-2-furanc...

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Detalhes bibliográficos
Principais autores: Zhou, L, Stewart, G, Rideau, E, Westwood, NJ, Smith, TK
Formato: Journal article
Idioma:English
Publicado em: American Chemical Society 2013