Learning to quantify uncertainty in off-target activity for CRISPR guide RNAs

CRISPR-based genome editing technologies have revolutionised the field of molecular biology, offering unprecedented opportunities for precise genetic manipulation. However, off-target effects remain a significant challenge, potentially leading to unintended consequences and limiting the applicabilit...

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Hlavní autoři: Ozden, F, Minary, P
Médium: Journal article
Jazyk:English
Vydáno: Oxford University Press 2024