Structural and functional consequences of age-related isomerization in α-crystallins

Structural and functional consequences of age-related isomerization in α-crystallins

Long-lived proteins are subject to spontaneous degradation and may accumulate a range of modifications over time, including subtle alterations such as side-chain isomerization. Recently, tandem MS has enabled identification and characterization of such peptide isomers, including those differing only...

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Dettagli Bibliografici
Autori principali:	Lyon, YA, Collier, MP, Riggs, DL, Degiacomi, MT, Benesch, JLP, Julian, RR
Natura:	Journal article
Lingua:	English
Pubblicazione:	American Society for Biochemistry and Molecular Biology 2019

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