Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease

Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease

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Chronic granulomatous disease (CGD) is an inherited disorder of phagocytes in which NADPH oxidase is defective in generating reactive oxygen species. In this study, we reprogrammed three normal unrelated patient's fibroblasts (p47phox and gp91phox) to pluripotency by lentiviral transduction wit...

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Detalles Bibliográficos
Autores principales:	Jiang, Y, Cowley, S, Siler, U, al., E
Formato:	Journal article
Lenguaje:	English
Publicado:	AlphaMed Press 2012

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