Pathogenic mechanisms in murine autoimmune thyroiditis: short- and long-term effects of in vivo depletion of CD4+ and CD8+ cells.
Both murine CD4+ and CD8+ cells are found in the thyroid infiltrate in experimental autoimmune thyroiditis (EAT) induced with mouse thyroglobulin (MTg). MTg activation of immune cells in vitro enables CD4+ cells to transfer thyroiditis adoptively and to aid the cytotoxic capacity of CD8+ cells for t...
المؤلفون الرئيسيون: | Kong, Y, Waldmann, H, Cobbold, S, Giraldo, A, Fuller, B, Simon, L |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
1989
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مواد مشابهة
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Depletion of CD4+ and CD8+ cells eliminates immunologic memory of thyroiditogenicity in murine experimental autoimmune thyroiditis.
حسب: Fuller, B, وآخرون
منشور في: (1994) -
Suppression in murine experimental autoimmune thyroiditis: in vivo inhibition of CD4+ T cell-mediated resistance by a nondepleting rat CD4 monoclonal antibody.
حسب: Nabozny, G, وآخرون
منشور في: (1991) -
INSITU ANALYSIS OF THYROID T-CELL INFILTRATES IN MURINE EXPERIMENTAL AUTOIMMUNE-THYROIDITIS (EAT)
حسب: Conaway, D, وآخرون
منشور في: (1987) -
TOLERANCE INDUCTION USING CD4 AND CD8 MONOCLONAL-ANTIBODIES
حسب: Waldmann, H, وآخرون
منشور في: (1989) -
Resistance to experimental autoimmune thyroiditis: L3T4+ cells as mediators of both thyroglobulin-activated and TSH-induced suppression.
حسب: Kong, Y, وآخرون
منشور في: (1989)