Pathogenic mechanisms in murine autoimmune thyroiditis: short- and long-term effects of in vivo depletion of CD4+ and CD8+ cells.

Both murine CD4+ and CD8+ cells are found in the thyroid infiltrate in experimental autoimmune thyroiditis (EAT) induced with mouse thyroglobulin (MTg). MTg activation of immune cells in vitro enables CD4+ cells to transfer thyroiditis adoptively and to aid the cytotoxic capacity of CD8+ cells for t...

詳細記述

書誌詳細
主要な著者: Kong, Y, Waldmann, H, Cobbold, S, Giraldo, A, Fuller, B, Simon, L
フォーマット: Journal article
言語:English
出版事項: 1989