Limited heterogeneity of the HLA class II contribution to susceptibility to rheumatoid arthritis is suggested by positive associations with HLA-DR4, DR1 and DRw10.

Most patients with rheumatoid arthritis (RA) exhibit an HLA class II epitope found on most DR4 and DR1 molecules. We have investigated the possibility of other associations being present in the minority of patients lacking these antigens. One hundred and eighty patients with classical or definite RA...

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Bibliographic Details
Main Authors: Wordsworth, B, Stedeford, J, Rosenberg, WM, Bell, J
Format: Journal article
Language:English
Published: 1991