AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum.

The beta-adrenergic receptor/cyclic AMP/protein kinase A (PKA) signalling pathway regulates heart rate and contractility. Here, we identified a supramolecular complex consisting of the sarcoplasmic reticulum Ca(2+)-ATPase (SERCA2), its negative regulator phospholamban (PLN), the A-kinase anchoring p...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Lygren, B, Carlson, C, Santamaria, K, Lissandron, V, McSorley, T, Litzenberg, J, Lorenz, D, Wiesner, B, Rosenthal, W, Zaccolo, M, Taskén, K, Klussmann, E
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2007