Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1).

BACKGROUND: Asthma is a common, chronic inflammatory airway disease of major public health importance with multiple genetic determinants. Previously, we found by positional cloning that PHD finger protein 11 (PHF11) on chromosome 13q14 modifies serum immunoglobulin E (IgE) concentrations and asthma...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Holt, R, Zhang, Y, Binia, A, Dixon, A, Vandiedonck, C, Cookson, W, Knight, J, Moffatt, M
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2011