Investigation into the onset and progression of transplant arteriosclerosis in a mice aortic retransplantation model.

Investigation into the onset and progression of transplant arteriosclerosis in a mice aortic retransplantation model.

Long-term function of vascularized human organ grafts is often limited by transplant arteriosclerosis and can lead to graft failure. Here, we have analyzed the impact of an initial rejection episode on the later development of transplant arteriosclerosis. Following transplantation of allogeneic abdo...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Steger, U, Ensminger, S, Bushell, A, Wood, K
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2008

Antzeko izenburuak

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Platelet-endothelial cell adhesion molecule-1 (CD31) expression on donor endothelial cells attenuates the development of transplant arteriosclerosis.
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Kinetics of transplant arteriosclerosis in MHC-Class I mismatched and fully allogeneic mouse aortic allografts.
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Critical role for IL-4 in the development of transplant arteriosclerosis in the absence of CD40-CD154 costimulation.
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Indirect allorecognition plays a pivotal role in the pathogenesis of transplant arteriosclerosis.
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Indirect allorecognition can play an important role in the development of transplant arteriosclerosis.
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CD8+ T cells contribute to the development of transplant arteriosclerosis despite CD154 blockade.
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Tadalafil attenuates graft arteriosclerosis of aortic transplant in a rat model
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Mouse endothelial CD40 expression does not play a role during the development of transplant arteriosclerosis.
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Eosinophils are major effector cells for the development of transplant arteriosclerosis and depend on the presence of IL-4.
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Increased transplant arteriosclerosis in the absence of CCR7 is associated with reduced expression of Foxp3.
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Intragraft interleukin-4 mRNA expression after short-term CD154 blockade may trigger delayed development of transplant arteriosclerosis in the absence of CD8+ T cells.
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