The pattern of localization of the putative oocyte activation factor, phospholipase Czeta, in uncapacitated, capacitated, and ionophore-treated human spermatozoa.

BACKGROUND: Recent studies suggest that in mammals, oocyte activation at fertilization is triggered by a sperm-specific phospholipase C, PLCzeta. We investigated PLCzeta localization in human spermatozoa. METHODS: A polyclonal antibody was generated against human PLCzeta and used in immunoblotting a...

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Main Authors: Grasa, P, Coward, K, Young, C, Parrington, J
格式: Journal article
語言:English
出版: 2008