Copper-catalysed synthesis of alkylidene 2-pyrrolinone derivatives from the combination of α-keto amides and alkynes

A Cu(I)-catalysed addition and cyclisation sequence has been developed for the synthesis of (E)-alkylidene pyrrolinone derivatives. The reactions incorporate simple α-keto amides and alkynes as substrates, and employ a commercially available Cu(I) catalyst. The process tolerates good variation of bo...

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Detaylı Bibliyografya
Asıl Yazarlar: Tan, Q, Chovatia, P, Willis, M
Materyal Türü: Journal article
Baskı/Yayın Bilgisi: Royal Society of Chemistry 2018

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