Pin1 in neuronal apoptosis.

While the role of the prolyl isomerase Pin1 in dividing cells has long been recognized, Pin1's function in postmitotic neurons is poorly understood. We have identified a novel mechanism by which Pin1 mediates activation of the mitochondrial cell death machinery specifically in neurons. This per...

Полное описание

Библиографические подробности
Главные авторы: Becker, E, Bonni, A
Формат: Journal article
Язык:English
Опубликовано: 2007