Pin1 in neuronal apoptosis.

While the role of the prolyl isomerase Pin1 in dividing cells has long been recognized, Pin1's function in postmitotic neurons is poorly understood. We have identified a novel mechanism by which Pin1 mediates activation of the mitochondrial cell death machinery specifically in neurons. This per...

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Bibliografiske detaljer
Main Authors: Becker, E, Bonni, A
Format: Journal article
Sprog:English
Udgivet: 2007