Pin1 in neuronal apoptosis.
While the role of the prolyl isomerase Pin1 in dividing cells has long been recognized, Pin1's function in postmitotic neurons is poorly understood. We have identified a novel mechanism by which Pin1 mediates activation of the mitochondrial cell death machinery specifically in neurons. This per...
Main Authors: | , |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
2007
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