Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine.

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine.

Adequate clinical and parasitologic cure by artemisinin combination therapies relies on the artemisinin component and the partner drug. Polymorphisms in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) and P. falciparum multidrug resistance 1 (pfmdr1) genes are associated with de...

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Main Authors: Venkatesan, M, Gadalla, N, Stepniewska, K, Dahal, P, Nsanzabana, C, Moriera, C, Price, R, Mårtensson, A, Rosenthal, P, Dorsey, G, Sutherland, C, Guérin, P, Davis, T, Ménard, D, Adam, I, Ademowo, G, Arze, C, Baliraine, F, Berens-Riha, N, Björkman, A, Borrmann, S, Checchi, F, Desai, M, Dhorda, M, Djimdé, A, El-Sayed, B, Eshetu, T, Eyase, F, Falade, C, Faucher, J, Fröberg, G, Grivoyannis, A, Hamour, S, Houzé, S, Johnson, J, Kamugisha, E, Kariuki, S, Kiechel, JR, Kironde, F, Kofoed, P, Lebras, J, Malmberg, M, Mwai, L, Ngasala, B, Nosten, F, Nsobya, S, Nzila, A, Oguike, M, Otienoburu, S, Ogutu, B, Ouédraogo, J, Piola, P, Rombo, L, Schramm, B, Somé, A, Thwing, J, Ursing, J, Wong, R, Zeynudin, A, Zongo, I, Plowe, C, Sibley, C
Format: Journal article
Language:English
Published: American Society of Tropical Medicine and Hygiene 2014

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