Kinetic analysis of matrix metalloproteinase activity using fluorogenic triple-helical substrates.

Kinetic analysis of matrix metalloproteinase activity using fluorogenic triple-helical substrates.

Matrix metalloproteinase (MMP) family members are involved in the physiological remodeling of tissues and embryonic development as well as pathological destruction of extracellular matrix components. To study the mechanisms of MMP action on collagenous substrates, we have constructed homotrimeric, f...

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Bibliographic Details
Main Authors:	Lauer-Fields, J, Broder, T, Sritharan, T, Chung, L, Nagase, H, Fields, G
Format:	Journal article
Language:	English
Published:	2001

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