Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Risk for late-onset Alzheimer's disease (LOAD), the most prevalent dementia, is partially driven by genetics. To identify LOAD risk loci, we performed a large genome-wide association meta-analysis of clinically diagnosed LOAD (94,437 individuals). We confirm 20 previous LOAD risk loci and ident...

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Bibliographic Details
Main Authors: Kunkle, BW, Grenier-Boley, B, Sims, R, Lovestone, S, Gallacher, J, Clarke, R, Smith, AD, Warden, D, Wilcock, G, al, E
Format: Journal article
Language:English
Published: Springer Nature 2019