Spatial transcriptomic characterization of COVID-19 pneumonitis identifies immune circuits related to tissue injury

Severe lung damage in COVID-19 involves complex interactions between diverse populations of immune and stromal cells. In this study, we used a spatial transcriptomics approach to delineate the cells, pathways and genes present across the spectrum of histopathological damage in COVID-19 lung tissue....

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Dettagli Bibliografici
Autori principali: Cross, AR, de Andrea, CE, María, V-E, Landecho Acha, MF, Cerundolo, L, Weeratunga, P, Etherington, R, Denney, L, Ogg, G, Ho, LP, Roberts, ISD, Hester, J, Klenerman, P, Melero, I, Sansom, SN, Issa, F
Natura: Journal article
Lingua:English
Pubblicazione: American Society for Clinical Investigation 2023