Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk.
BACKGROUND: Somatic mutations in phosphoinositide-3-kinase catalytic subunit alpha (PIK3CA) are frequent in breast tumours and have been associated with oestrogen receptor (ER) expression, human epidermal growth factor receptor-2 overexpression, lymph node metastasis and poor survival. The goal of...
المؤلفون الرئيسيون: | , , , , , , , , , , , , , , , , , , , , , , , , |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2011
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