Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk.

Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk.

BACKGROUND: Somatic mutations in phosphoinositide-3-kinase catalytic subunit alpha (PIK3CA) are frequent in breast tumours and have been associated with oestrogen receptor (ER) expression, human epidermal growth factor receptor-2 overexpression, lymph node metastasis and poor survival. The goal of...

書目詳細資料
Main Authors:	Stevens, K, Garcia-Closas, M, Fredericksen, Z, Kosel, M, Pankratz, V, Hopper, J, Dite, G, Apicella, C, Southey, M, Schmidt, M, Broeks, A, Van 't Veer, L, Tollenaar, R, Fasching, P, Beckmann, M, Hein, A, Ekici, AB, Johnson, N, Peto, J, dos Santos Silva, I, Gibson, L, Sawyer, E, Tomlinson, I, Kerin, M, Chanock, S
格式:	Journal article
語言:	English
出版:	2011

相似書籍

Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium.
由: Figueroa, J, et al.
出版: (2011)

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium.
由: Warren, H, et al.
出版: (2012)

11q13 is a susceptibility locus for hormone receptor positive breast cancer
由: Lambrechts, D, et al.
出版: (2012)

11q13 is a susceptibility locus for hormone receptor positive breast cancer.
由: Lambrechts, D, et al.
出版: (2012)

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.
由: Lin, W, et al.
出版: (2015)

Phosphoinositide Profile of the Mouse Retina
由: Stella Finkelstein, et al.
出版: (2020-06-01)

Molecular Mechanisms of Human Disease Mediated by Oncogenic and Primary Immunodeficiency Mutations in Class IA Phosphoinositide 3-Kinases
由: Gillian L. Dornan, et al.
出版: (2018-03-01)

Phosphoinositide Lipids in Ocular Tissues
由: Ammaji Rajala, et al.
出版: (2020-06-01)

Phosphoinositides in Retinal Function and Disease
由: Theodore G. Wensel
出版: (2020-04-01)

Respiratory Manifestations of the Activated Phosphoinositide 3-Kinase Delta Syndrome
由: Alison M. Condliffe, et al.
出版: (2018-03-01)

Spatial regulation of membrane fusion controlled by modification of phosphoinositides.
由: Fabrice Dumas, et al.
出版: (2010-01-01)

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.
由: Meyer, K, et al.
出版: (2013)

Phosphoinositides and intracellular calcium signaling: novel insights into phosphoinositides and calcium coupling as negative regulators of cellular signaling
由: Byung-Chul Oh
出版: (2023-08-01)

A mathematical model of the phosphoinositide pathway
由: Olivença, DV, et al.
出版: (2018)

Phosphoinositide signalling in inflammation and colorectal cancer
由: Osborne, C, et al.
出版: (2003)

Phosphoinositide signalling in inflammation and colorectal cancer
由: Osborne, C, et al.
出版: (2003)

Phosphoinositides Coated Beads Binding Assay
由: Manuel Gálvez-Santisteban, et al.
出版: (2014-02-01)

Phosphoinositide Signaling in Immune Cell Migration
由: Ruchi Kakar, et al.
出版: (2023-11-01)

Regulation of phosphoinositide metabolism in Apicomplexan parasites
由: Angela Arabiotorre, et al.
出版: (2023-09-01)

Participation of the phosphoinositide metabolism in the hypersensitive response of Citrus limon against Alternaria alternata
由: XIMENA ORTEGA, et al.
出版: (2001-01-01)

Deleterious Variants of FIG4, a Phosphoinositide Phosphatase, in Patients with ALS
由: Chow, Clement Y., et al.
出版: (2015)

Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)
由: Xueqin Huang, et al.
出版: (2023-12-01)

Comparing the frequency of common genetic variants and haplotypes between carriers and non-carriers of <it>BRCA1 </it>and <it>BRCA2 </it>deleterious mutations in Australian women diagnosed with breast cancer before 40 years of age
由: Turkovic Lidija, et al.
出版: (2010-09-01)

Oncogenes /
由: 311669 Cooper, Geoffrey M.
出版: (1995)

3-Phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer
由: Fyffe C, et al.
出版: (2013-08-01)

Liposome Flotation Assays for Phosphoinositide-protein Interaction
由: Helene Tronchere, et al.
出版: (2017-03-01)

Regulation of the Phosphoinositide Code by Phosphorylation of Membrane Readers
由: Troy A. Kervin, et al.
出版: (2021-05-01)

Nuclear Phosphoinositides as Key Determinants of Nuclear Functions
由: Magdalena C. Vidalle, et al.
出版: (2023-06-01)

Regulation of Phosphoinositide Signaling by Scaffolds at Cytoplasmic Membranes
由: Tianmu Wen, et al.
出版: (2023-08-01)

Phosphoinositides in plant-pathogen interaction: trends and perspectives
由: Fauzia Zarreen, et al.
出版: (2023-04-01)

Nuclear Phosphoinositides—Versatile Regulators of Genome Functions
由: Enrique Castano, et al.
出版: (2019-06-01)

Phosphoinositides in the Hepatitis C Virus Life Cycle
由: Aleem Siddiqui, et al.
出版: (2012-10-01)

The expanding spectrum of neurological disorders of phosphoinositide metabolism
由: Jonathan R. Volpatti, et al.
出版: (2019-08-01)

Phosphoinositide Signaling and Mechanotransduction in Cardiovascular Biology and Disease
由: Amanda Krajnik, et al.
出版: (2020-12-01)

Phosphoinositide 3-kinase: a critical signalling event in pulmonary cells
由: Cowburn Andrew S, et al.
出版: (2000-06-01)

Targeting phosphoinositide signaling in cancer: relevant techniques to study lipids and novel avenues for therapeutic intervention
由: Alicia Llorente, et al.
出版: (2023-10-01)

Expression of phosphoinositide-specific phospholipase C isoforms in native endothelial cells.
由: Delphine M Béziau, et al.
出版: (2015-01-01)

Signaling through non-membrane nuclear phosphoinositide binding proteins in human health and disease
由: Jamal M. Bryant, et al.
出版: (2019-02-01)

Superresolution Microscopy Reveals Distinct Phosphoinositide Subdomains Within the Cilia Transition Zone
由: Sarah E. Conduit, et al.
出版: (2021-04-01)

Phosphoinositide-3-Kinase Signaling in Human Natural Killer Cells: New Insights from Primary Immunodeficiency
由: Emily M. Mace
出版: (2018-03-01)