HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice.

This study investigated the effects of 2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido) acetic acid (IOX3), a selective small molecule inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylases, on mouse brains subject to transient focal cerebral ischaemia. Male, 8- to 12-week-old C57/B6 mice w...

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Váldodahkkit:	Chen, R, Ogunshola, O, Yeoh, K, Jani, A, Papadakis, M, Nagel, S, Schofield, C, Buchan, A
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2014

HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice Dahkki Chen, R, Ogunshola, O, Yeoh, K, Jani, A, Papadakis, M, Nagel, S, Schofield, C, Buchan, A

Almmustuhtton 2014

Journal article

HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice.

HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice Dahkki Chen, R, Ogunshola, O, Yeoh, K, Jani, A, Papadakis, M, Nagel, S, Schofield, C, Buchan, A

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