HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice.

This study investigated the effects of 2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido) acetic acid (IOX3), a selective small molecule inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylases, on mouse brains subject to transient focal cerebral ischaemia. Male, 8- to 12-week-old C57/B6 mice w...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Chen, R, Ogunshola, O, Yeoh, K, Jani, A, Papadakis, M, Nagel, S, Schofield, C, Buchan, A
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2014