Mechanism of diol dehydration by a promiscuous radical‐SAM enzyme homologue of the antiviral enzyme viperin (RSAD2)
3´‐deoxy nucleotides are an important class of drugs because they interfere with metabolism of nucleotides and their incorporation into DNA or RNA terminates cell division and viral replication. These compounds have largely been produced via multistep chemical synthesis and an enzyme with the abilit...
Main Authors: | Honarmand Ebrahimi, K, Rowbotham, J, McCullagh, J, James, W |
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Format: | Journal article |
Language: | English |
Published: |
Wiley
2020
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