Biological therapies for asthma

Biological therapies for asthma

Five to 10% of asthma patients remain symptomatic and/or have asthma attacks despite adequate inhaled and systemic therapy. Eosinophilic, type 2 airway inflammation is seen in half of these patients with severe asthma. There is now convincing evidence that type 2 inflammation drives susceptibility t...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Couillard Castonguay, S, Pavord, I
Kolejni autorzy:	Janes, S
Format:	Book section
Język:	English
Wydane:	Elsevier 2021

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Fractional exhaled nitric oxide non-suppression in asthma
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Predicting the benefits of type-2 targeted anti-inflammatory treatment with the prototype OxfoRd Asthma attaCk risk scaLE (ORACLE)
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Fluticasone furoate: CAPTAIN of fluticasones in type 2 inflammatory asthma
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Asthma in pregnancy: An update
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How I do it: workup of severe asthma
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Bronchial thermoplasty and biological therapy as targeted treatments for severe uncontrolled asthma
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Utility of adherence checks in patients with severe asthma eligible for biologics: a single centre retrospective analysis
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Type 2 inflammation and biological therapies in asthma: targeted medicine taking flight
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Emerging biologics in severe asthma
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Pharmacokinetic optimisation of inhaled steroid therapy in asthma.
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Blood eosinophils, fractional exhaled nitric oxide, and the risk of asthma attacks in randomised controlled trials: protocol for a systemic review and control arm patient-level meta-analysis for clinical prediction modelling
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A proof-of-concept scale to predict asthma attacks: the OxfoRd Asthma attaCk risk ScaLE (ORACLE)
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Derivation of a prototype asthma attack risk scale centred on blood eosinophils and exhaled nitric oxide
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Blood eosinophils, fractional exhaled nitric oxide and the risk of asthma attacks in randomised controlled trials: protocol for a systemic review and control arm patient-level meta-analysis for clinical prediction modelling
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Step 4: stick or twist? A review of step 4 asthma therapy
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Cycling biologic therapy for severe asthma
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Biologic Therapy and Severe Asthma in Children
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Azithromycin in uncontrolled asthma
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Controversies in allergy: should severe asthma with eosinophilic phenotype always be treated with anti-IL-5 therapies
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Asthma control, airway responsiveness and airway inflammation.
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Non-eosinophilic asthma and the innate immune response.
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Mepolizumab, quality of life, and severe eosinophilic asthma.
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FeNO non-suppression identifies corticosteroid-resistant type-2 signaling in severe asthma
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Longitudinal changes in sputum and blood inflammatory mediators during FeNO suppression testing
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Stability of inflammatory phenotypes in asthma.
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Eosinophils in asthma and airway hyperresponsiveness.
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