Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer.

Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer.

Recent genome-wide association studies (GWASs) have identified common variants at 16 autosomal regions influencing the risk of developing colorectal cancer (CRC). To decipher the genetic basis of the association signals at these loci, we performed a meta-analysis of data from five GWASs, totalling 5...

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Bibliographic Details
Main Authors: Whiffin, N, Dobbins, SE, Hosking, F, Palles, C, Tenesa, A, Wang, Y, Farrington, S, Jones, A, Broderick, P, Campbell, H, Newcomb, P, Casey, G, Conti, D, Schumacher, F, Gallinger, S, Lindor, N, Hopper, J, Jenkins, M, Dunlop, MG, Tomlinson, I, Houlston, R
Format: Journal article
Language:English
Published: 2013

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