CD8+ T cell responses to human immunodeficiency viruses type 2 (HIV-2) and type 1 (HIV-1) gag proteins are distinguishable by magnitude and breadth but not cellular phenotype.

CD8+ T cell responses to human immunodeficiency viruses type 2 (HIV-2) and type 1 (HIV-1) gag proteins are distinguishable by magnitude and breadth but not cellular phenotype.

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The mechanisms underlying the relatively slow progression of human immunodeficiency virus type 2 (HIV-2) compared with HIV-1 infection are undefined and could be a result of more effective immune responses. We used HIV-2 and HIV-1 IFN-gamma enzyme-linked immunospot assays to evaluate CD8(+) T cell r...

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Bibliographic Details
Main Authors: Gillespie, G, Pinheiro, S, Sayeid-Al-Jamee, M, Alabi, A, Kaye, S, Sabally, S, Sarge-Njie, R, Njai, H, Joof, K, Jaye, A, Whittle, H, Rowland-Jones, S, Dorrell, L
Format: Journal article
Language:English
Published: 2005

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