Temperature stability of proteins essential for the intracellular survival of Mycobacterium tuberculosis.
In Mycobacterium tuberculosis, the genes hsaD (2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase) and nat (arylamine N-acetyltransferase) are essential for survival inside of host macrophages. These genes act as an operon and have been suggested to be involved in cholesterol metabolism. Howeve...
Main Authors: | Lack, N, Kawamura, A, Fullam, E, Laurieri, N, Beard, S, Russell, A, Evangelopoulos, D, Westwood, I, Sim, E |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
2009
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Lignende værker
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Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis.
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Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.
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Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages
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Structure and mechanism of arylamine N-acetyltransferases.
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Udgivet: (2021-04-01)