Temperature stability of proteins essential for the intracellular survival of Mycobacterium tuberculosis.
In Mycobacterium tuberculosis, the genes hsaD (2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase) and nat (arylamine N-acetyltransferase) are essential for survival inside of host macrophages. These genes act as an operon and have been suggested to be involved in cholesterol metabolism. Howeve...
Главные авторы: | Lack, N, Kawamura, A, Fullam, E, Laurieri, N, Beard, S, Russell, A, Evangelopoulos, D, Westwood, I, Sim, E |
---|---|
Формат: | Journal article |
Язык: | English |
Опубликовано: |
2009
|
Схожие документы
-
Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis.
по: Fullam, E, и др.
Опубликовано: (2009) -
Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.
по: Sim, E, и др.
Опубликовано: (2008) -
Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages
по: Abuhammad, A, и др.
Опубликовано: (2012) -
Structure and mechanism of arylamine N-acetyltransferases.
по: Westwood, I, и др.
Опубликовано: (2006) -
Discovery of uncompetitive inhibitors of SapM that compromise intracellular survival of Mycobacterium tuberculosis
по: Paulina Fernández-Soto, и др.
Опубликовано: (2021-04-01)